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Proceedings Paper

Grid-less imaging with antiscatter correction software in 2D mammography: the effects on image quality and MGD under a partial virtual clinical validation study
Author(s): Nelis Van Peteghem; Frédéric Bemelmans; Xenia Bramaje Adversalo; Elena Salvagnini; Nicholas Marshall; Hilde Bosmans; Chantal Van Ongeval
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Paper Abstract

This work investigated the effect of the grid-less acquisition mode with scatter correction software developed by Siemens Healthcare (PRIME mode) on image quality and mean glandular dose (MGD) in a comparative study against a standard mammography system with grid. Image quality was technically quantified with contrast-detail (c-d) analysis and by calculating detectability indices (d’) using a non-prewhitening with eye filter model observer (NPWE). MGD was estimated technically using slabs of PMMA and clinically on a set of 11439 patient images. The c-d analysis gave similar results for all mammographic systems examined, although the d’ values were slightly lower for the system with PRIME mode when compared to the same system in standard mode (-2.8% to -5.7%, depending on the PMMA thickness). The MGD values corresponding to the PMMA measurements with automatic exposure control indicated a dose reduction from 11.0% to 20.8% for the system with PRIME mode compared to the same system without PRIME mode. The largest dose reductions corresponded to the thinnest PMMA thicknesses. The results from the clinical dosimetry study showed an overall population-averaged dose reduction of 11.6% (up to 27.7% for thinner breasts) for PRIME mode compared to standard mode for breast thicknesses from 20 to 69 mm. These technical image quality measures were then supported using a clinically oriented study whereby simulated clusters of microcalcifications and masses were inserted into patient images and read by radiologists in an AFROC study to quantify their detectability. In line with the technical investigation, no significant difference was found between the two imaging modes (p-value 0.95).

Paper Details

Date Published: 29 March 2016
PDF: 6 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97832K (29 March 2016); doi: 10.1117/12.2216690
Show Author Affiliations
Nelis Van Peteghem, KU Leuven (Belgium)
Frédéric Bemelmans, KU Leuven (Belgium)
Xenia Bramaje Adversalo, KU Leuven (Belgium)
Elena Salvagnini, KU Leuven (Belgium)
Nicholas Marshall, UZ Leuven (Belgium)
Hilde Bosmans, UZ Leuven (Belgium)
Chantal Van Ongeval, UZ Leuven (Belgium)

Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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