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Proceedings Paper

Discrimination between normal breast tissue and tumor tissue using CdTe series detector developed for photon-counting mammography
Author(s): Chizuru Okamoto; Akiko Ihori; Tsutomu Yamakawa; Shuichiro Yamamoto; Masahiro Okada; Misa Kato; Ai Nakajima; Yoshie Kodera
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Paper Abstract

We propose a new mammography system using a cadmium telluride (CdTe) series photon-counting detector, having high absorption efficiency over a wide energy range. In a previous study, we showed that the use of high X-ray energy in digital mammography is useful from the viewpoint of exposure dose and image quality. In addition, the CdTe series detector can acquire X-ray spectrum information following transmission through a subject. This study focused on the tissue composition identified using spectral information obtained by a new photon-counting detector. Normal breast tissue consists entirely of adipose and glandular tissues. However, it is very difficult to find tumor tissue in the region of glandular tissue via a conventional mammogram, especially in dense breast because the attenuation coefficients of glandular tissue and tumor tissue are very close. As a fundamental examination, we considered a simulation phantom and showed the difference between normal breast tissue and tumor tissue of various thicknesses in a three-dimensional (3D) scatter plot. We were able to discriminate between both types of tissues. In addition, there was a tendency for the distribution to depend on the thickness of the tumor tissue. Thinner tumor tissues were shown to be closer in appearance to normal breast tissue. This study also demonstrated that the difference between these tissues could be made obvious by using a CdTe series detector. We believe that this differentiation is important, and therefore, expect this technology to be applied to new tumor detection systems in the future.

Paper Details

Date Published: 29 March 2016
PDF: 6 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97832G (29 March 2016); doi: 10.1117/12.2216447
Show Author Affiliations
Chizuru Okamoto, Nagoya Univ. Graduate School of Medicine (Japan)
Akiko Ihori, Nagoya Univ. Graduate School of Medicine (Japan)
Tsutomu Yamakawa, JOB Corp. (Japan)
Shuichiro Yamamoto, JOB Corp. (Japan)
Masahiro Okada, JOB Corp. (Japan)
Misa Kato, Nagoya Univ. (Japan)
Ai Nakajima, Nagoya Univ. (Japan)
Yoshie Kodera, Nagoya Univ. Graduate School of Medicine (Japan)

Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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