Share Email Print

Proceedings Paper

Classification of SD-OCT volumes for DME detection: an anomaly detection approach
Author(s): S. Sankar; D. Sidibé; Y. Cheung; T. Y. Wong; E. Lamoureux; D. Milea; F. Meriaudeau
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Diabetic Macular Edema (DME) is the leading cause of blindness amongst diabetic patients worldwide. It is characterized by accumulation of water molecules in the macula leading to swelling. Early detection of the disease helps prevent further loss of vision. Naturally, automated detection of DME from Optical Coherence Tomography (OCT) volumes plays a key role. To this end, a pipeline for detecting DME diseases in OCT volumes is proposed in this paper. The method is based on anomaly detection using Gaussian Mixture Model (GMM). It starts with pre-processing the B-scans by resizing, flattening, filtering and extracting features from them. Both intensity and Local Binary Pattern (LBP) features are considered. The dimensionality of the extracted features is reduced using PCA. As the last stage, a GMM is fitted with features from normal volumes. During testing, features extracted from the test volume are evaluated with the fitted model for anomaly and classification is made based on the number of B-scans detected as outliers. The proposed method is tested on two OCT datasets achieving a sensitivity and a specificity of 80% and 93% on the first dataset, and 100% and 80% on the second one. Moreover, experiments show that the proposed method achieves better classification performances than other recently published works.

Paper Details

Date Published: 24 March 2016
PDF: 6 pages
Proc. SPIE 9785, Medical Imaging 2016: Computer-Aided Diagnosis, 97852O (24 March 2016); doi: 10.1117/12.2216215
Show Author Affiliations
S. Sankar, Univ. de Bourgogne (France)
D. Sidibé, Univ. de Bourgogne (France)
Y. Cheung, Singapore Eye Research Institute (Singapore)
T. Y. Wong, Singapore Eye Research Institute (Singapore)
E. Lamoureux, Singapore Eye Research Institute (Singapore)
D. Milea, Singapore Eye Research Institute (Singapore)
F. Meriaudeau, Univ. de Bourgogne (France)

Published in SPIE Proceedings Vol. 9785:
Medical Imaging 2016: Computer-Aided Diagnosis
Georgia D. Tourassi; Samuel G. Armato III, Editor(s)

© SPIE. Terms of Use
Back to Top