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Proceedings Paper

Scattering-compensated cone beam x-ray luminescence computed tomography
Author(s): Peng Gao; Junyan Rong; Huangsheng Pu; Wenlei Liu; Qimei Liao; Hongbing Lu
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Paper Abstract

X-ray luminescence computed tomography (XLCT) opens new possibilities to perform molecular imaging with x-ray. It is a dual modality imaging technique based on the principle that some nanophosphors can emit near-infrared (NIR) light when excited by x-rays. The x-ray scattering effect is a great issue in both CT and XLCT reconstruction. It has been shown that if the scattering effect compensated, the reconstruction average relative error can be reduced from 40% to 12% in the in the pencil beam XLCT. However, the scattering effect in the cone beam XLCT has not been proved. To verify and reduce the scattering effect, we proposed scattering-compensated cone beam x-ray luminescence computed tomography using an added leading to prevent the spare x-ray outside the irradiated phantom in order to decrease the scattering effect. Phantom experiments of two tubes filled with Y2O3:Eu3+ indicated that the proposed method could reduce the scattering by a degree of 30% and can reduce the location error from 1.8mm to 1.2mm. Hence, the proposed method was feasible to the general case and actual experiments and it is easy to implement.

Paper Details

Date Published: 1 April 2016
PDF: 6 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 978354 (1 April 2016); doi: 10.1117/12.2214919
Show Author Affiliations
Peng Gao, Fourth Military Medical Univ. (China)
Junyan Rong, Fourth Military Medical Univ. (China)
Huangsheng Pu, Fourth Military Medical Univ. (China)
Wenlei Liu, Fourth Military Medical Univ. (China)
Qimei Liao, Fourth Military Medical Univ. (China)
Hongbing Lu, Fourth Military Medical Univ. (China)

Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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