A method based on a modified inverse Radon transform is presented to correct photoacoustic and laser-ultrasound section images taken with a cylindrical integrating detector for heterogeneity in the speed of sound. Data for the correction are obtained with a laser ultrasound transmission method, providing two-dimensional maps of the speed of sound distribution. Photoacoustic, laser ultrasound and speed of sound tomography are combined in a single setup using illumination of the sample and several external absorbers with short pulses from a single laser source. The performance of the corrected reconstruction is compared in a simulation and a phantom experiment with a reconstruction using an average, constant sound speed. In this comparison, the reconstruction using the modified inverse Radon transform shows a small but distinguishable improvement.

Date Published: 16 July 2015
PDF: 6 pages
Proc. SPIE 9539, Opto-Acoustic Methods and Applications in Biophotonics II, 953917 (16 July 2015); doi: 10.1117/12.2183873

Published in SPIE Proceedings Vol. 9539:
Opto-Acoustic Methods and Applications in Biophotonics II
Vasilis Ntziachristos; Roger Zemp, Editor(s)