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Proceedings Paper

Performance improvement by a broadband super-luminescent diode light source in 1.7-µm spectroscopic spectral-domain optical coherence tomography for lipid distribution imaging in a coronary artery
Author(s): M. Tanaka; T. Okuno; H. Obi; I. Hattori; M. Hirano; T. Ueno; S. Tonosaki; K. Murashima; R. Yamaguchi; T. Hasegawa
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Paper Abstract

We develop a 1.7-μm optical coherence tomography (OCT) system using a broadband light source based on superluminescent diodes (SLDs) and investigated the possibility of plaque detection by a spectroscopic OCT (S-OCT) method. The SLD-based light source realizes an output power about 20mW and a 3-dB bandwidth over 120nm for optimization of driving current in each SLD. Regarding performance of the 1.7-μm spectral-domain OCT system with the light source, the system sensitivity is 104dB in maximum at the A-scan rate of 47kHz, which is fifty times as high as that in the previous study with a super-continuum light source. Moreover, we perform visualization of lipid distribution at the A-scan frame of 47kHz by an in-vitro artery model which is made of a piece of porcine coronary artery and a lardfilled nylon tube as a plaque phantom. We confirm that the sensitivity and specificity between artery and plaque area in optimal condition for lipid detection at a specific frame image is over 90% and there are high lipid scores at the inside of plaque phantom in other frame images at the same condition. It indicates the possibility of plaque detection in intravascular OCT.

Paper Details

Date Published: 4 March 2014
PDF: 9 pages
Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89262T (4 March 2014); doi: 10.1117/12.2038866
Show Author Affiliations
M. Tanaka, Sumitomo Electric Industries, Ltd. (Japan)
T. Okuno, Sumitomo Electric Industries, Ltd. (Japan)
H. Obi, Sumitomo Electric Industries, Ltd. (Japan)
I. Hattori, Sumitomo Electric Industries, Ltd. (Japan)
M. Hirano, Sumitomo Electric Industries, Ltd. (Japan)
T. Ueno, Sumitomo Electric Industries, Ltd. (Japan)
S. Tonosaki, Sumitomo Electric Industries, Ltd. (Japan)
K. Murashima, Sumitomo Electric Industries, Ltd. (Japan)
R. Yamaguchi, Sumitomo Electric Industries, Ltd. (Japan)
T. Hasegawa, Sumitomo Electric Industries, Ltd. (Japan)


Published in SPIE Proceedings Vol. 8926:
Photonic Therapeutics and Diagnostics X
Bernard Choi; Hyun Wook Kang; Brian J. F. Wong M.D.; Guillermo J. Tearney M.D.; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory M.D.; Justus F. Ilgner M.D.; Haishan Zeng; Laura Marcu, Editor(s)

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