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Proceedings Paper

Automated localization of wrinkles and the dermo-epidermal junction in obliquely oriented reflectance confocal microscopic images of human skin
Author(s): Jamshid Sourati; Kivanc Kose; Milind Rajadhyaksha; Jennifer G. Dy; Deniz Erdogmus; Dana H. Brooks
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Paper Abstract

Reflectance Confocal Microscopic (RCM) imaging of obliquely-oriented optical sections, rather than with traditional z-stacks, shows depth information that more closely mimics the appearance of skin in orthogonal sections of histology. This approach may considerably reduce the amount of data that must be acquired and processed. However, as with z-stacks, purely visual detection of the dermal-epidermal junction (DEJ) in oblique images remains challenging. Here, we have extended our original algorithm for localization of DEJ in z-stacks to oblique images. In addition, we developed an algorithm for detecting wrinkles, which in addition to its intrinsic merit, gives useful information for DEJ detection.

Paper Details

Date Published: 22 February 2013
PDF: 9 pages
Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 856503 (22 February 2013); doi: 10.1117/12.2006489
Show Author Affiliations
Jamshid Sourati, Northeastern Univ. (United States)
Kivanc Kose, Memorial Sloan-Kettering Cancer Ctr. (United States)
Milind Rajadhyaksha, Memorial Sloan-Kettering Cancer Ctr. (United States)
Jennifer G. Dy, Northeastern Univ. (United States)
Deniz Erdogmus, Northeastern Univ. (United States)
Dana H. Brooks, Northeastern Univ. (United States)


Published in SPIE Proceedings Vol. 8565:
Photonic Therapeutics and Diagnostics IX
Andreas Mandelis; Brian Jet-Fei Wong; Anita Mahadevan-Jansen; Henry Hirschberg M.D.; Hyun Wook Kang; Nikiforos Kollias; Melissa J. Suter; Kenton W. Gregory M.D.; Guillermo J. Tearney M.D.; Stephen Lam; Bernard Choi; Steen J. Madsen; Bodo E. Knudsen M.D.; E. Duco Jansen; Justus F. Ilgner M.D.; Haishan Zeng; Matthew Brenner; Laura Marcu, Editor(s)

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