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Proceedings Paper

Confocal microscopy to guide laser ablation of basal cell carinoma: a preliminary feasibility study
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Paper Abstract

Laser ablation may be a promising method for removal of skin lesions, with the potential for better cosmetic outcomes and reduced scarring and infection. An obstacle to implementing laser ablation is that the treatment leaves no tissue for histopathological analysis. Pre-operative and intra-operative mapping of BCCs using confocal microscopy may guide the ablation of the tumor until all tumor is removed. We demonstrate preliminary feasibility of confocal microscopy to guide laser ablation of BCCs in freshly excised tissue from Mohs surgery. A 2940 nm Er:YAG laser provides efficient ablation of tumor with reduced thermal damage to the surrounding tissue.

Paper Details

Date Published: 8 March 2013
PDF: 7 pages
Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 856502 (8 March 2013); doi: 10.1117/12.2005482
Show Author Affiliations
Bjorg A. Larson, Drew Univ. (United States)
Memorial Sloan-Kettering Cancer Ctr. (United States)
Heidy Sierra, Memorial Sloan-Kettering Cancer Ctr. (United States)
Jason Chen, Memorial Sloan-Kettering Cancer Ctr. (United States)
Milind Rajadhyaksha, Memorial Sloan-Kettering Cancer Ctr. (United States)

Published in SPIE Proceedings Vol. 8565:
Photonic Therapeutics and Diagnostics IX
Andreas Mandelis; Brian Jet-Fei Wong; Anita Mahadevan-Jansen; Henry Hirschberg M.D.; Hyun Wook Kang; Nikiforos Kollias; Melissa J. Suter; Kenton W. Gregory M.D.; Guillermo J. Tearney M.D.; Stephen Lam; Bernard Choi; Steen J. Madsen; Bodo E. Knudsen M.D.; E. Duco Jansen; Justus F. Ilgner M.D.; Haishan Zeng; Matthew Brenner; Laura Marcu, Editor(s)

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