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Proceedings Paper

Influence of tissue treatment onto the Raman spectra obtained from prostate histopathological slides for diagnostic purposes
Author(s): Jason Wander; Sinisa Vukelic
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Paper Abstract

In recent years, Raman spectroscopy has emerged as a potentially viable tool for automated cancer diagnostics. However, due to the complexity of the signal obtained from a tissue, most of the studies have been confined to statistical analysis of the spectra with principal component analysis being most often reported as the analysis of choice. These types of analyses are sensitive to modification of the Raman spectra due to tissue processing. The study presented here addresses the modifications of the Raman spectra obtained from prostate tissue histopathological slides due to the tissue treatment and its influence on the automated cancer diagnostics via Raman spectroscopy.

Paper Details

Date Published: 8 March 2013
PDF: 9 pages
Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 85651F (8 March 2013); doi: 10.1117/12.2003406
Show Author Affiliations
Jason Wander, Bucknell Univ. (United States)
Sinisa Vukelic, Bucknell Univ. (United States)

Published in SPIE Proceedings Vol. 8565:
Photonic Therapeutics and Diagnostics IX
Andreas Mandelis; Brian Jet-Fei Wong; Anita Mahadevan-Jansen; Henry Hirschberg M.D.; Hyun Wook Kang; Nikiforos Kollias; Melissa J. Suter; Kenton W. Gregory M.D.; Guillermo J. Tearney M.D.; Stephen Lam; Bernard Choi; Steen J. Madsen; Bodo E. Knudsen M.D.; E. Duco Jansen; Justus F. Ilgner M.D.; Haishan Zeng; Matthew Brenner; Laura Marcu, Editor(s)

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