Multiscale Imaging and Spectroscopy VI

Multiscale imaging and spectroscopy are increasing in popularity as groups discover they need to better link structure and function, slow and fast dynamics, physiological and molecular scales, and translational and mechanistic viewpoints. While biologist have pushed for higher resolution and faster imaging, a broader spatial or temporal context is often needed to fully characterize most complex biological systems. Additionally, as cutting-edge imaging and spectroscopy techniques acquire increasingly large data sets, there has been a drive to develop tools to visualize and identify relevant features on a variety of spatial and temporal scales.

This conference will bring together optical tool developers, basic scientists, and clinicians to present advances in multiscale imaging. Topics include the development and applications of single and multi-modality techniques that characterize biological systems over multiple temporal, spatial, or contrast scales.

Technologies include but are not limited to the following:

• diffuse optical spectroscopy, imaging, and tomography
• lightsheet microscopy
• structured illumination microscopy
• multiphoton imaging
• optical coherence tomography
• photoacoustic imaging
• Raman, fluorescence, and absorption spectroscopy
• functional and anatomical imaging
• optical contrast agent development
• photodynamic therapy.

Applications include, but are not limited to the following:

• longitudinal monitoring of disease progression or therapy response
• optical methods to assess tissue biomechanical structure and function
• wide-field, high-resolution imaging
• visualization and analysis of large multiscale data sets
• multiscale views of neural activity, tumor biology, and immune response
• integration of preclinical and clinical data sets
• methods to integrate functional and structural optical data sets
• fractal analysis of multiscale imaging data sets.