The Moscone Center
San Francisco, California, United States
1 - 6 February 2020
Conference 11250
High-Speed Biomedical Imaging and Spectroscopy V
Saturday - Tuesday 1 - 4 February 2020
Conference
Committee
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Conference Chairs
Program Committee
  • Steven G. Adie, Cornell Univ. (United States)
  • Mohammad Hossein Asghari, Loyola Marymount Univ. (United States)
  • Hongwei Chen, Tsinghua Univ. (China)
  • Pei-Yu Eric Chiou, Univ. of California, Los Angeles (United States)
  • Shi-Wei Chu, National Taiwan Univ. (Taiwan)
  • Qionghai Dai, Tsinghua Univ. (China)
  • Mark Foster, Johns Hopkins Univ. (United States)
  • Katsumasa Fujita, Osaka Univ. (Japan)
  • Liang Gao, Univ. of Illinois at Urbana-Champaign (United States)
  • Nobuyuki Hashimoto, Citizen Watch Co., Ltd. (Japan)
  • Elena Holden, Executive Strategic Advisory, Biotech and IVD (United States)
  • Bahram Jalali, Univ. of California, Los Angeles (United States)
  • Chulhong Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
  • Thomas Klein, Optores GmbH (Germany)
  • Edmund Y. Lam, The Univ. of Hong Kong (Hong Kong, China)
  • Cheng Lei, Wuhan Univ. (China)

Program Committee continued...
Saturday 1 February Show All Abstracts
Opening Remarks
Saturday 1 February 2020
8:20 AM - 8:30 AM

Opening remarks by Conference Chair Kevin Tsia
Session 1:
High-Speed Volumetric Imaging
Saturday 1 February 2020
8:30 AM - 10:00 AM
Session Chair:
Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
Epi-illumination SPIM (eSPIM) for high-throughput volumetric imaging (Invited Paper)
Paper 11250-1
Author(s): Bo Huang, Univ. of California, San Francisco (United States), Chan Zuckerberg Biohub (United States)
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Visualizing dynamic biological processes using light-field microscopy (Invited Paper)
Paper 11250-2
Author(s): Robert Prevedel, European Molecular Biology Lab. (Germany)
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Multiplanes line-scanning confocal microscopy for high-speed fluorescence imaging
Paper 11250-3
Author(s): Jean-Marc Tsang, Jerome Mertz, Boston Univ. (United States)
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Ultrafast contour imaging for time-domain diffuse optical tomography
Paper 11250-4
Author(s): Xiaohua Feng, Liang Gao, Univ. of Illinois (United States)
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Session 2:
High-Speed Fluorescence Imaging
Saturday 1 February 2020
10:30 AM - 12:00 PM
Session Chair:
Adrian G. H. Podoleanu, Univ. of Kent (United Kingdom)
A compact device for ultra-fast whole-cell/tissue FLIM and hyper-spectral imaging (Invited Paper)
Paper 11250-5
Author(s): Michelle Digman, Univ. of California, Irvine (United States)
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Simple chemical stains for feature-rich super-resolution and cleared-tissue microscopy (Invited Paper)
Paper 11250-6
Author(s): Joshua Vaughan, Univ. of Washington (United States)
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SLIDE: Spectro-temporal encoded FLIM at 2kHz frame-rate
Paper 11250-7
Author(s): Sebastian Karpf, Univ. zu Lübeck (Germany); Bahram Jalali, Univ. of California, Los Angeles (United States)
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Optical gearbox for kHz frame rate imaging
Paper 11250-8
Author(s): Meng Cui, Purdue Univ. (United States)
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Lunch Break 12:00 PM - 1:30 PM
Session 3:
High-throughput Microscopy
Saturday 1 February 2020
1:30 PM - 3:15 PM
Simultaneous multiplane imaging with reverberation multiphoton microscopy (Invited Paper)
Paper 11250-9
Author(s): Jerome Mertz, Devin Beaulieu, Ian Davison, Thomas Bifano, Boston Univ. (United States)
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High-speed super-resolution imaging of intracellular organelle interactions (Invited Paper)
Paper 11250-10
Author(s): Dong Li, Institute of Biophysics (China)
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A widefield mid-infrared photothermal microscope for chemical imaging at kHz frame rate and sub-micron spatial resolution
Paper 11250-11
Author(s): Yeran Bai, Delong Zhang, Boston Univ. (United States); Ali Shakouri, Purdue Univ. (United States); Ji-Xin Cheng, Boston Univ. (United States)
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High-throughput and field-portable ptychographic lensless microscopy based on translated pattern modulation
Paper 11250-12
Author(s): Guoan Zheng, Univ. of Connecticut (United States)
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Multi-megahertz spectrally encoded transmission microscopy based on dual-comb interferometry
Paper 11250-13
Author(s): Xinglin Zeng, Yu-xuan Ren, Pingping Feng, Yuhua Duan, The Univ. of Hong Kong (Hong Kong, China); Chi Zhang, Huazhong Univ. of Science and Technology (China); Kevin K. Tsia, Kenneth Kin-Yip Wong, The Univ. of Hong Kong (Hong Kong, China)
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Session 4:
Imaging Flow Cytometry
Saturday 1 February 2020
3:45 PM - 5:45 PM
Session Chair:
Keisuke Goda, The Univ. of Tokyo (Japan)
High-throughput analysis of cell physical properties (Invited Paper)
Paper 11250-14
Author(s): Dino Di Carlo, Univ. of California, Los Angeles (United States)
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Image guided FACS and 3D imaging flow cytometer (Invited Paper)
Paper 11250-15
Author(s): Yu-Hwa Lo, Univ. of California, San Diego (United States)
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High-speed single-cell quantitative phase imaging integrated with real-time deformability cytometry
Paper 11250-16
Author(s): Evelyn H. Y. Cheung, Rashmi Sreeramachandramurthy, Dickson M. D. Siu, Kelvin C. M. Lee, The Univ. of Hong Kong (Hong Kong, China); Martin Kraeter, Max-Planck-Institut für die Physik des Lichts (Germany); Felix Reichel, TU Dresden (Germany); Jochen Guck, Max-Planck-Institut für die Physik des Lichts (Germany); Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Image-based cell sorting using artificial intelligence classification
Paper 11250-17
Author(s): Maik Herbig, Ahmad Ahsan Nawaz, Martin Nötzel, Marta Urbanska, Martin Kräter, Philipp Rosendahl, Angela Jacobi, TU Dresden (Germany); Oliver Otto, TU Dresden (Germany), Ernst Moritz Arndt Univ. Greifswald (Germany), Zellmechanik Dresden GmbH (Germany); Christoph Herold, Zellmechanik Dresden GmbH (Germany); Jochen Guck, TU Dresden (Germany)
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Compressed ultrafast imaging flow cytometry
Paper 11250-18
Author(s): Jongchan Park, Liang Gao, Univ. of Illinois (United States)
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FluorATOM: high-throughput imaging flow cytometry for synchronized biophysical and biomolecular phenotyping
Paper 11250-19
Author(s): Kelvin C. M. Lee, Maolin Wang, Isabella Cheuk, Vivian Shine, Ava Kwong, Kenneth Kin-Yip Wong, Hayden So, Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Session HT:
BiOS Hot Topics
Saturday 1 February 2020
7:00 PM - 9:00 PM
Sunday 2 February Show All Abstracts
Session 5:
High-Throughput Biology
Sunday 2 February 2020
8:30 AM - 10:00 AM
Session Chair:
Liang Gao, Univ. of Illinois (United States)
Adaptive optics for diffraction limited two-photon imaging of neuronal function throughout the full depth of mouse cortex (Invited Paper)
Paper 11250-20
Author(s): David Kleinfeld, Rui Liu, Univ. of California, San Diego (United States)
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Probing the spatiotemporal dynamics of Ras-associated membrane nanodomains with high-throughput single particle tracking via photoactivated localization microscopy (spt-PALM) (Invited Paper)
Paper 11250-21
Author(s): Yerim Lee, Carey Phelps, Tao Huang, Barmak Mostofian, Daniel Zuckerman, Xiaolin Nan, Oregon Health & Science Univ. (United States)
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Visualization of membrane potential changes induced by oscillating electric fields
Paper 11250-22
Author(s): Allen Kiester, Zach Coker, Bennett Ibey, Joel Bixler, Air Force Research Lab. (United States)
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High-speed label-free photoacoustic histopathology
Paper 11250-23
Author(s): Jin Woo Baik, Jin Young Kim, Hyojin Kim, Pohang Univ. of Science and Technology (Korea, Republic of); Myeongjoo Son, Kyunghee Byun, Gachon Univ. of Medicine and Science (Korea, Republic of); Hae Young Choi, Daegu-Gyeongbuk Medical Innovation Foundation (Korea, Republic of); Seon Young Ryu, Panovision Co., Ltd. (Korea, Republic of); Chulhong Kim, Pohang Univ. of Science and Technology (Korea, Republic of)
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Session 6:
High-Speed Raman Technologies
Sunday 2 February 2020
10:30 AM - 12:00 PM
Session Chair:
Eric O. Potma, Univ. of California, Irvine (United States)
Compressive Raman imaging (Invited Paper)
Paper 11250-24
Author(s): Hervé Rigneault, Aix-Marseille Univ. (France), Ecole Centrale de Marseille (France), CNRS (France); Camille Scotte, Siddharth Sivankutty, Aix-Marseille Univ. (France); Randy Bartels, Colorado State Univ. (United States)
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High-sensitivity stimulated Raman imaging with chemical tags (Invited Paper)
Paper 11250-25
Author(s): Lu Wei, Caltech (United States)
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High-throughput multimodal Raman-fluorescence flow cytometry
Paper 11250-26
Author(s): Matthew Lindley, The Univ. of Tokyo (Japan); Kotaro Hiramatsu, The Univ. of Tokyo (Japan), PRESTO, Japan Science and Technology Agency (Japan); Fukashi Shibata, Tsuyoshi Takeshita, Algal Bio Co., Ltd. (Japan); Shigeyuki Kawano, The Univ. of Tokyo (Japan); Keisuke Goda, The Univ. of Tokyo (Japan), Univ. of California. Los Angeles (United States), The Institute of Technological Sciences, Wuhan Univ. (China)
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Rapid monitoring of pharmacokinetics of mitochondria-targeting molecules in live cells with bioorthogonal hyperspectral stimulated Raman scattering microscopy
Paper 11250-27
Author(s): Kideog Bae, Wei Zheng, Zhiwei Huang, Optical Bioimaging Lab. (Singapore)
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Lunch Break 12:00 PM - 1:30 PM
Session 7:
Machine Learning
Sunday 2 February 2020
1:30 PM - 3:15 PM
Session Chair:
Kotaro Hiramatsu, The Univ. of Tokyo (Japan)
Computational augmentations of single molecule super-resolution microscopy (Invited Paper)
Paper 11250-28
Author(s): Christophe Zimmer, Institut Pasteur (France)
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Pushing the limits of fluorescence microscopy with adaptive imaging and machine learning (Invited Paper)
Paper 11250-29
Author(s): Loic Royer, Chan Zuckerberg Biohub (United States)
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Classification of platelet aggregates by intelligent imaging flow cytometry
Paper 11250-30
Author(s): Yuqi Zhou, Atsushi Yasumoto, The Univ. of Tokyo (Japan); Cheng Lei, Wuhan Univ. (China); Chun-Jung Huang, National Chiao Tung Univ. (Taiwan); Hirofumi Kobayashi, Chan Zuckerberg Biohub (United States); Yunzhao Wu, Sheng Yan, The Univ. of Tokyo (Japan); Chia-Wei Sun, National Chiao Tung Univ. (Taiwan); Yutaka Yatomi, Keisuke Goda, The Univ. of Tokyo (Japan)
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High throughput label-free optical hemogram of granulocytes enhanced by artificial neural networks
Paper 11250-31
Author(s): Roopam K. Gupta, Mingzhou Chen, Univ. of St. Andrews (United Kingdom); Graeme P. A. Malcolm, Nils Hempler, M Squared Lasers Ltd. (United Kingdom); Kishan Dholakia, Simon Powis, Univ. of St. Andrews (United Kingdom)
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Simple, rapid and cost-effective drug-susceptibility testing of leukemia by intelligent whole-blood imaging flow cytometry
Paper 11250-32
Author(s): Hirofumi Kobayashi, The Univ. of Tokyo (Japan), Chan Zuckerberg Biohub (United States); Cheng Lei, The Univ. of Tokyo (Japan), Wuhan Univ. (China); Yi Wu, The Univ. of Tokyo (Japan), Univ. of Toronto (Canada); Chun-Jung Huang, The Univ. of Tokyo (Japan), National Chiao Tung Univ. (Taiwan); Atsushi Yasumoto, Masahiro Jona, The Univ. of Tokyo (Japan); Wenxuan Li, Carnegie Mellon Univ. (United States); Yaxiaer Yalikun, Ctr. for Biosystems Dynamics Research, RIKEN (Japan); Baoshan Guo, The Univ. of Tokyo (Japan); Chia-Wei Sun, National Chiao Tung Univ. (Taiwan); Yo Tanaka, Ctr. for Biosystems Dynamics Research, RIKEN (Japan); Makoto Yamada, Ctr. for Advanced Intelligence Project, RIKEN (Japan); Yutaka Yatomi, The Univ. of Tokyo (Japan); Keisuke Goda, The Univ. of Tokyo (Japan), Wuhan Univ. (China), Univ. of California, Los Angeles (United States)
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Session 8:
High-Throughput Technologies
Sunday 2 February 2020
3:45 PM - 5:45 PM
Session Chair:
Guoan Zheng, Univ. of Connecticut (United States)
Acquiring fluorescence decay kinetic measurements with on-chip acoustic focusing cytometry (Invited Paper)
Paper 11250-33
Author(s): Jessica P. Houston, Jesus Sambrano, Kevin D. Houston, Saptasree Bose, Concepcion Sanchez, New Mexico State Univ. (United States)
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High-speed tracking of proteins on a live cell membrane via iSCAT (Invited Paper)
Paper 11250-34
Author(s): Vahid Sandoghdar, Max-Planck-Institut für die Physik des Lichts (Germany)
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Single-shot compressed ultrafast holography
Paper 11250-35
Author(s): Ruibo Shang, Geoffrey Luke, Thayer School of Engineering at Dartmouth (United States)
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Continuous high-resolution observation system using high-speed gaze and focus control with wide-angle triangulation
Paper 11250-36
Author(s): Tomohiro Sueishi, The Univ. of Tokyo (Japan); Takuya Ogawa, Shoji Yachida, NEC Corp. (Japan); Masatoshi Ishikawa, The Univ. of Tokyo (Japan)
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Rapid, robust, and low-cost whole slide imaging system based on LED-array illumination and color-multiplexed single-shot autofocusing
Paper 11250-37
Author(s): Shaowei Jiang, Zichao Bian, Chengfei Guo, Guoan Zheng, Univ. of Connecticut (United States)
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Towards high-speed fourier ptychographic imaging using binary measurements on a SPAD camera
Paper 11250-38
Author(s): Xi Yang, Pavan Chandra Konda, Roarke Horstmeyer, Duke Univ. (United States)
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Closing Remarks
Sunday 2 February 2020
5:45 PM - 5:55 PM

Closing remarks by Conference Chair Keisuke Goda
Session PSun:
Posters-Sunday
Sunday 2 February 2020
5:30 PM - 7:00 PM

Conference attendees are invited to attend the BiOS poster session on Sunday evening. Come view the posters, enjoy light refreshments, ask questions, and network with colleagues in your field.

Poster Setup: Sunday 10:00 AM – 4:30 PM
View poster presentation guidelines and set-up instructions at
http://spie.org/PWPosterGuidelines
Ultrahigh-throughput rendering of digital holograms for real-time laser Doppler ophthalmoscopy and Gabor microscopy
Paper 11250-40
Author(s): Michael Atlan, Leo Puyo, Louis Pallegoix, Julie Rivet, Institut Langevin Ondes et Images (France)
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Application of post optical amplification for scan-less confocal amplitude and phase imaging with dual-comb microscopy
Paper 11250-41
Author(s): Takahiko Mizuno, Takuya Tsuda, Eiji Hase, Takeo Minamikawa, Institute of Post-LED Photonics, Tokushima Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan); Hirotsugu Yamamoto, Utsunomiya Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan); Takeshi Yasui, Institute of Post-LED Photonics, Tokushima Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan)
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Full-field dual-comb fluorescence lifetime microscopy
Paper 11250-42
Author(s): Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Institute of Post-LED Photonics, Tokushima Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan); Hirotsugu Yamamoto, Utsunomiya Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan); Takeshi Yasui, Institute of Post-LED Photonics, Tokushima Univ. (Japan), JST-ERATO MINOSHIMA Intelligent Optical Synthesizer Project (Japan)
Show Abstract
Session PLN:
BiOS Sunday Plenary
Sunday 2 February 2020
7:15 PM - 8:00 PM
Tuesday 4 February Show All Abstracts
Session 9:
Quantitative Phase Imaging and High-Speed Biomedical Imaging and Spectroscopy: Joint Session with 11249 and 11250
Tuesday 4 February 2020
8:00 AM - 9:40 AM
Quantitative phase imaging and artificial intelligence: label-free 3D imaging, classification, and inference (Invited Paper)
Paper 11249-45
Author(s): YongKeun Park, KAIST (Korea, Republic of)
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Deep single-cell biophysical phenotyping with high-throughput quantitative phase imaging (Invited Paper)
Paper 11249-46
Author(s): Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Big-data reconstruction of 3D refractive index by multi-slice beam-propagation
Paper 11249-47
Author(s): Shwetadwip Chowdhury, David Ren, James Cimino, Laura Waller, Univ. of California, Berkeley (United States)
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Towards reliable deep learning based phase microscopy
Paper 11250-39
Author(s): Yujia Xue, Shiyi Cheng, Yunzhe Li, Lei Tian, Boston Univ. (United States)
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